Vicissitude
(noun) 1a. The quality or state of being changeable b. natural change or mutation visible in nature or in human affairs c. a difficulty or hardship attendant on a way of life, a career, or a course of action and usually beyond one's control
Cecil has always looked like a grown man in the face. He had a scar under his eye from falling off his bike, his hair line has been receding since the 3rd grade, and he has had facial hair since elementary school. His appearance has greatly affected by the vicissitudes of life.

